Category: CagA

Topic: Cytotoxin-Associated Gene A (CagA)

CagA (Cytotoxin-Associated Gene A) CagA/E-cadherin interaction ExpSup: CagA Induces P21 Expression ExpSup: CagA Induces β-catenin Relocalization from Cell Membrane to…

CagA (Cytotoxin-Associated Gene A)

CagA (Cytotoxin-Associated Gene A) is a protein encoded by the cagA gene found in specific strains of Helicobacter pylori, which…

ExpSup: CagA Induces P21 Expression

Murata-Kamiya et al., 2007 showed that cagA expression in MKN-28 cell line results in upregulation of p21WAF1/Cip1 using western blotting….

ExpSup: CagA Induces Cyclin D1 Expression

Murata-Kamiya et al., 2007 showed that cagA expression in MKN-28 cell line results in upregulation of cyclin D1 using western…

ExpSup: CagA Activates β-catenin in Tyrosine-phosphorylation Independent Manner

β-catenin is usually present in the plasma membrane at cell-cell junctions in a complex called adherens junction. Upon activation, β-catenin…

ExpSup: CagA Physically Interacts with E-cadherin in Tyrosine-phosphorylation Independent Manner

Murata-Kamiya et al., 2007 showed that E-cadherin physically interacts with CagA protein using co-immunoprecipitation in cell lysate prepared from MKN-28…

CagA/E-cadherin interaction

CagA physically interacts with E-cadherin and this interaction is independent of CagA tyrosine phosphorylation status (Murata-Kamiya et al., 2007).  …