Category: Nucleophosmin

Express relatively high level of p53 and p21 Undergo senescence (early passage cells) Post-mitotic tetraploid cell-cycle arrest and polyploidy Aberrant…

Embryonic lethal, die between E11.5 and E12.5 (Grisendi et al., 2005)

NPM is important for the oncogenic functions of c-Myc. Its overexpression enhances the hyperproliferation and transformation driven by c-Myc, while…

Nucleophosmin (NPM) plays a significant role in cell transformation, particularly through its interaction with c-Myc. In their 2008 study, Li…

Note: The protein nucleophosmin is commonly referred to as NPM or NPM1 in the literature. Nucleophosmin can enhance cell proliferation. …

Note: The protein nucleophosmin is commonly referred to as NPM or NPM1 in the literature. The protein Nucleophosmin is primarily…

Synonyms: Nucleophosmin/B23 Nucleophosmin Numatrin B23 NPM NPM1 NO38 Note: NPM1 is commonly referred to as nucleophosmin, while other nucleophosmins like…