Lab Notes: Virology Archives - Laboratory Notes https://www.laboratorynotes.com/category/lab-notes-virology/ Tue, 25 Aug 2026 06:53:34 +0000 en hourly 1 https://wordpress.org/?v=7.1 LGP2 https://www.laboratorynotes.com/lgp2/ https://www.laboratorynotes.com/lgp2/#respond Tue, 25 Aug 2026 06:53:34 +0000 https://www.laboratorynotes.com/?p=29837 LGP2 is a regulatory RNA sensor that modulates the activity of RIG‑I and MDA5 rather than directly activating antiviral signalling. By stabilising MDA5 filaments and fine‑tuning RIG‑I responses, LGP2 ensures precise detection of viral RNA and prevents harmful immune overactivation.

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