Cancer Archives - Laboratory Notes https://www.laboratorynotes.com/tag/cancer/ Wed, 30 Sep 2026 21:21:41 +0000 en hourly 1 https://wordpress.org/?v=7.1.2 MYC Oncoprotein https://www.laboratorynotes.com/myc-oncoprotein/ https://www.laboratorynotes.com/myc-oncoprotein/#respond Wed, 30 Sep 2026 21:21:41 +0000 https://www.laboratorynotes.com/?p=32484 MYC oncoproteins are powerful transcription factors that reprogram gene expression to promote cancer cell growth, proliferation, metabolism and survival. Discover how MYC, MYCN and MYCL contribute to tumor development.

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]]> https://www.laboratorynotes.com/myc-oncoprotein/feed/ 0 RAS Oncoprotein https://www.laboratorynotes.com/ras-oncoprotein/ https://www.laboratorynotes.com/ras-oncoprotein/#respond Wed, 30 Sep 2026 20:17:32 +0000 https://www.laboratorynotes.com/?p=32482 RAS oncoproteins are powerful cancer-driving proteins that act as abnormal molecular switches. Mutations in KRAS, NRAS and HRAS can keep RAS signaling active, promoting cell proliferation, survival, metabolism, invasion and tumor progression.

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]]> https://www.laboratorynotes.com/ras-oncoprotein/feed/ 0 How Oncogenes Are Activated: Mutation, Amplification, Overexpression and Chromosomal Rearrangement https://www.laboratorynotes.com/how-oncogenes-are-activated-mutation-amplification-overexpression-and-chromosomal-rearrangement/ https://www.laboratorynotes.com/how-oncogenes-are-activated-mutation-amplification-overexpression-and-chromosomal-rearrangement/#respond Wed, 30 Sep 2026 20:09:54 +0000 https://www.laboratorynotes.com/?p=32479 Oncogenes can arise when proto-oncogenes are activated by mutations, gene amplification, overexpression or chromosomal rearrangements. These changes can produce persistent signaling and cancer-driving oncoproteins.

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]]> https://www.laboratorynotes.com/how-oncogenes-are-activated-mutation-amplification-overexpression-and-chromosomal-rearrangement/feed/ 0 Proto-Oncogenes and Oncogenes https://www.laboratorynotes.com/proto-oncogenes-and-oncogenes/ https://www.laboratorynotes.com/proto-oncogenes-and-oncogenes/#respond Wed, 30 Sep 2026 19:55:33 +0000 https://www.laboratorynotes.com/?p=32476 Proto-oncogenes are normal genes that regulate cell growth, survival and signaling. Genetic alterations can convert them into oncogenes that produce or promote cancer-driving oncoproteins.

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]]> https://www.laboratorynotes.com/proto-oncogenes-and-oncogenes/feed/ 0 Oncoprotein https://www.laboratorynotes.com/oncoprotein/ https://www.laboratorynotes.com/oncoprotein/#respond Wed, 30 Sep 2026 19:34:28 +0000 https://www.laboratorynotes.com/?p=32473 Oncoproteins are abnormal or deregulated proteins that promote cancer development by altering cell proliferation, survival, metabolism, signaling, and other cellular processes. This overview introduces major types of oncoproteins and their roles in cancer.

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]]> https://www.laboratorynotes.com/oncoprotein/feed/ 0 Ubiquitin–Proteasome System (UPS) in Cancer https://www.laboratorynotes.com/ubiquitin-proteasome-system-ups-in-cancer/ https://www.laboratorynotes.com/ubiquitin-proteasome-system-ups-in-cancer/#comments Tue, 18 Aug 2026 23:00:39 +0000 https://www.laboratorynotes.com/?p=29652 The ubiquitin–proteasome system (UPS) regulates protein turnover and controls cell‑cycle progression, DNA repair, apoptosis and oncogenic signalling. In cancer, UPS components become dysregulated, leading to excessive degradation of tumour suppressors and stabilisation of oncogenic proteins. This imbalance drives tumour growth and makes UPS a powerful therapeutic target.

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]]> https://www.laboratorynotes.com/ubiquitin-proteasome-system-ups-in-cancer/feed/ 1 Cancer https://www.laboratorynotes.com/cancer/ https://www.laboratorynotes.com/cancer/#comments Mon, 17 Aug 2026 08:49:36 +0000 https://www.laboratorynotes.com/?p=29479 Cancer is a multifaceted disease caused by the uncontrolled growth of abnormal cells. It develops through genetic and epigenetic alterations, environmental exposures, and interactions within the tumour microenvironment. Understanding these processes is essential for improving prevention, diagnosis, and treatment.

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