Cdc25B Archives - Laboratory Notes https://www.laboratorynotes.com/tag/cdc25b/ Wed, 26 Aug 2026 08:01:37 +0000 en hourly 1 https://wordpress.org/?v=7.1.2 Cdc25 https://www.laboratorynotes.com/cdc25/ https://www.laboratorynotes.com/cdc25/#comments Wed, 19 Aug 2026 15:26:51 +0000 https://www.laboratorynotes.com/?p=29708 Cdc25 phosphatases activate CDKs to drive both the G1–S and G2–M transitions. By removing inhibitory phosphates from CDK1 and CDK2, Cdc25 triggers DNA replication and mitotic entry. Checkpoint kinases such as Chk1 inhibit Cdc25 during DNA damage, while Cdc25 overexpression promotes genomic instability and contributes to tumour progression.

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