Cellular senescence Archives - Laboratory Notes https://www.laboratorynotes.com/tag/cellular-senescence/ Wed, 26 Aug 2026 08:00:32 +0000 en hourly 1 https://wordpress.org/?v=7.1.2 Premature Ageing https://www.laboratorynotes.com/premature-ageing/ https://www.laboratorynotes.com/premature-ageing/#comments Thu, 20 Aug 2026 19:46:08 +0000 https://www.laboratorynotes.com/?p=29753 Premature ageing describes the accelerated decline of cellular and physiological functions caused by genomic instability, telomere attrition, mitochondrial dysfunction and chronic inflammation. These processes activate ageing pathways earlier than expected, leading to early onset of tissue deterioration, reduced homeostasis and increased vulnerability to age‑related diseases.

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]]> https://www.laboratorynotes.com/premature-ageing/feed/ 1 Ageing https://www.laboratorynotes.com/ageing/ https://www.laboratorynotes.com/ageing/#comments Thu, 20 Aug 2026 19:20:48 +0000 https://www.laboratorynotes.com/?p=29749 Ageing is a gradual biological process driven by genomic instability, telomere shortening, mitochondrial dysfunction and cellular senescence. These changes reduce physiological resilience, impair tissue repair and increase susceptibility to chronic disease. Understanding the mechanisms of ageing provides insight into longevity, healthspan and the development of age‑related disorders.

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