Chaperones Archives - Laboratory Notes https://www.laboratorynotes.com/tag/chaperones/ Wed, 26 Aug 2026 00:02:22 +0000 en hourly 1 https://wordpress.org/?v=7.1 Protein Quality Control https://www.laboratorynotes.com/protein-quality-control/ https://www.laboratorynotes.com/protein-quality-control/#respond Wed, 26 Aug 2026 00:02:22 +0000 https://www.laboratorynotes.com/?p=29884 Protein quality control (PQC) is a cellular surveillance system that preserves proteome integrity by monitoring protein folding, repairing misfolded proteins and eliminating damaged or aggregated species. Through coordinated action of chaperones, the ubiquitin–proteasome system and autophagy, PQC protects cells from proteotoxic stress and maintains homeostasis.

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