Exon skipping Archives - Laboratory Notes

Splice-Site Mutation

admin — Tue, 15 Sep 2026 00:23:21 +0000

Splice-site mutations are genetic variants that disrupt the signals required for accurate RNA splicing. They can cause exon skipping, intron retention, cryptic splice-site activation, abnormal mRNA production, and changes in protein expression.

The post Splice-Site Mutation appeared first on Laboratory Notes.

Alternative 5′ and 3′ Splice Site

admin — Tue, 15 Sep 2026 00:05:11 +0000

Alternative 5′ and 3′ splice sites allow cells to select different boundaries during RNA splicing, producing mature RNA transcripts with different structures. Learn how spliceosomes, splicing factors, and regulatory sequences control alternative splice-site selection and influence gene expression.

The post Alternative 5′ and 3′ Splice Site appeared first on Laboratory Notes.

Exon Skipping

admin — Mon, 14 Sep 2026 23:53:16 +0000

Exon skipping is a form of alternative RNA splicing in which one or more exons are excluded from mature mRNA. Learn how splice sites, splicing factors, and regulatory elements control exon inclusion and skipping and how this process affects gene expression and protein diversity.

The post Exon Skipping appeared first on Laboratory Notes.