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	<title>Hsp70 ATPase cycle Archives - Laboratory Notes</title>
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		<title>Hsp70 Nucleotide Exchange Factors: How NEFs Reset the Chaperone Cycle</title>
		<link>https://www.laboratorynotes.com/hsp70-nucleotide-exchange-factors-how-nefs-reset-the-chaperone-cycle/</link>
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		<dc:creator><![CDATA[admin]]></dc:creator>
		<pubDate>Fri, 11 Sep 2026 20:36:07 +0000</pubDate>
				<category><![CDATA[Lab Notes]]></category>
		<category><![CDATA[Lab Notes: Cell Biology]]></category>
		<category><![CDATA[Lab Notes: Protein Science]]></category>
		<category><![CDATA[BAG proteins]]></category>
		<category><![CDATA[Heat shock proteins]]></category>
		<category><![CDATA[Hsp110]]></category>
		<category><![CDATA[Hsp70]]></category>
		<category><![CDATA[Hsp70 ATPase]]></category>
		<category><![CDATA[Hsp70 ATPase cycle]]></category>
		<category><![CDATA[Hsp70 nucleotide exchange factors]]></category>
		<category><![CDATA[Molecular chaperones]]></category>
		<category><![CDATA[Nucleotide exchange factors]]></category>
		<category><![CDATA[Protein folding]]></category>
		<category><![CDATA[Protein quality control]]></category>
		<category><![CDATA[Proteostasis]]></category>
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					<description><![CDATA[<p>Hsp70 nucleotide exchange factors regulate the transition from ADP-bound to ATP-bound Hsp70, resetting the chaperone cycle and controlling substrate release. Learn how NEFs such as BAG proteins, Hsp110, HspBP1, and GrpE regulate Hsp70 activity and protein quality control.</p>
<p>The post <a href="https://www.laboratorynotes.com/hsp70-nucleotide-exchange-factors-how-nefs-reset-the-chaperone-cycle/">Hsp70 Nucleotide Exchange Factors: How NEFs Reset the Chaperone Cycle</a> appeared first on <a href="https://www.laboratorynotes.com">Laboratory Notes</a>.</p>
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