Inflammation Archives - Laboratory Notes https://www.laboratorynotes.com/tag/inflammation/ Sat, 12 Sep 2026 15:31:55 +0000 en hourly 1 https://wordpress.org/?v=7.1.2 Linoleic Acid: Sources, Functions & Health Effects https://www.laboratorynotes.com/linoleic-acid-sources-functions-health-effects/ https://www.laboratorynotes.com/linoleic-acid-sources-functions-health-effects/#respond Sat, 12 Sep 2026 15:31:55 +0000 https://www.laboratorynotes.com/?p=31044 Linoleic acid is an essential omega-6 fatty acid found in nuts, seeds and vegetable oils. Learn about its sources, functions, metabolism and health effects.

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]]> https://www.laboratorynotes.com/linoleic-acid-sources-functions-health-effects/feed/ 0 Omega-6 Fatty Acids: Sources, Functions & Health Effects https://www.laboratorynotes.com/omega-6-fatty-acids-sources-functions-health-effects/ https://www.laboratorynotes.com/omega-6-fatty-acids-sources-functions-health-effects/#respond Sat, 12 Sep 2026 14:01:49 +0000 https://www.laboratorynotes.com/?p=31036 Omega-6 fatty acids are important polyunsaturated fats found in vegetable oils, nuts and seeds. Learn about linoleic acid, sources, functions and health effects.

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]]> https://www.laboratorynotes.com/omega-6-fatty-acids-sources-functions-health-effects/feed/ 0 Protein Succinylation https://www.laboratorynotes.com/protein-succinylation/ https://www.laboratorynotes.com/protein-succinylation/#respond Mon, 31 Aug 2026 07:01:47 +0000 https://www.laboratorynotes.com/?p=30161 Protein succinylation is a metabolic post-translational modification that connects succinyl-CoA metabolism with protein function, mitochondrial activity, epigenetic regulation, gene expression and cellular homeostasis.

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]]> https://www.laboratorynotes.com/protein-succinylation/feed/ 0 Protein S-Glutathionylation https://www.laboratorynotes.com/protein-s-glutathionylation/ https://www.laboratorynotes.com/protein-s-glutathionylation/#respond Sun, 30 Aug 2026 15:43:02 +0000 https://www.laboratorynotes.com/?p=30167 Protein S-glutathionylation is a reversible cysteine modification that connects glutathione metabolism with redox signaling, oxidative stress responses, protein function, mitochondrial biology and disease.

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]]> https://www.laboratorynotes.com/protein-s-glutathionylation/feed/ 0 Protein Formylation https://www.laboratorynotes.com/protein-formylation/ https://www.laboratorynotes.com/protein-formylation/#respond Sun, 30 Aug 2026 13:01:15 +0000 https://www.laboratorynotes.com/?p=30164 Protein formylation is a chemical modification involved in bacterial and mitochondrial protein synthesis, protein maturation, innate immunity, inflammation and cellular signaling.

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]]> https://www.laboratorynotes.com/protein-formylation/feed/ 0 Protein Lactylation https://www.laboratorynotes.com/protein-lactylation/ https://www.laboratorynotes.com/protein-lactylation/#respond Sun, 30 Aug 2026 11:46:09 +0000 https://www.laboratorynotes.com/?p=30157 Protein lactylation is an emerging post-translational modification that connects lactate metabolism with protein regulation, gene expression, inflammation, cellular signaling and disease.

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]]> https://www.laboratorynotes.com/protein-lactylation/feed/ 0 Protein Citrullination https://www.laboratorynotes.com/protein-citrullination/ https://www.laboratorynotes.com/protein-citrullination/#respond Sat, 29 Aug 2026 23:11:33 +0000 https://www.laboratorynotes.com/?p=30149 Protein citrullination is a calcium-dependent post-translational modification that converts arginine into citrulline. Explore PAD enzymes, histone citrullination, NETosis, inflammation, rheumatoid arthritis, autoimmunity, cancer, and citrullination proteomics.

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]]> https://www.laboratorynotes.com/protein-citrullination/feed/ 0 Chronic Inflammation https://www.laboratorynotes.com/chronic-inflammation/ https://www.laboratorynotes.com/chronic-inflammation/#respond Sat, 29 Aug 2026 11:48:39 +0000 https://www.laboratorynotes.com/?p=30106 Chronic inflammation is a long-lasting immune response that can affect tissues and contribute to various health conditions. Learn about its causes, symptoms, effects, diagnosis, and management.

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]]> https://www.laboratorynotes.com/chronic-inflammation/feed/ 0 Acute Inflammation https://www.laboratorynotes.com/acute-inflammation/ https://www.laboratorynotes.com/acute-inflammation/#respond Sat, 29 Aug 2026 09:12:54 +0000 https://www.laboratorynotes.com/?p=30102 Acute inflammation is a rapid, short-term response to injury or infection. Learn about its causes, symptoms, inflammatory cells, immune response, resolution, and role in healing.

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]]> https://www.laboratorynotes.com/acute-inflammation/feed/ 0 Inflammation https://www.laboratorynotes.com/inflammation/ https://www.laboratorynotes.com/inflammation/#respond Fri, 28 Aug 2026 21:45:54 +0000 https://www.laboratorynotes.com/?p=30099 Inflammation is a natural response to injury, infection, and other harmful stimuli. Learn about its types, causes, symptoms, immune mechanisms, healing, and effects on health.

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]]> https://www.laboratorynotes.com/inflammation/feed/ 0 Necroptosis https://www.laboratorynotes.com/necroptosis/ https://www.laboratorynotes.com/necroptosis/#respond Fri, 28 Aug 2026 10:33:18 +0000 https://www.laboratorynotes.com/?p=30065 Necroptosis is a regulated necrotic cell‑death pathway driven by RIPK1–RIPK3–MLKL signalling. Through membrane permeabilisation and inflammatory activation, necroptosis eliminates infected or damaged cells when apoptosis is blocked, shaping immunity and disease progression.

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]]> https://www.laboratorynotes.com/necroptosis/feed/ 0 RIPK1 https://www.laboratorynotes.com/ripk1/ https://www.laboratorynotes.com/ripk1/#respond Fri, 28 Aug 2026 10:19:09 +0000 https://www.laboratorynotes.com/?p=30067 RIPK1 is a central signalling kinase that determines whether a cell survives, undergoes apoptosis or triggers necroptosis. Through context‑dependent interactions with TNFR1, caspase‑8, RIPK3 and MLKL, RIPK1 integrates inflammatory cues and stress signals to regulate cell fate.

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]]> https://www.laboratorynotes.com/ripk1/feed/ 0 RIPK3 https://www.laboratorynotes.com/ripk3/ https://www.laboratorynotes.com/ripk3/#respond Fri, 28 Aug 2026 10:03:07 +0000 https://www.laboratorynotes.com/?p=30069 RIPK3 is a central necroptotic kinase that phosphorylates MLKL and drives regulated necrotic cell death. Through necrosome formation with RIPK1 and activation of inflammatory signalling, RIPK3 shapes immunity, tissue injury and disease progression.

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]]> https://www.laboratorynotes.com/ripk3/feed/ 0 MLKL https://www.laboratorynotes.com/mlkl/ https://www.laboratorynotes.com/mlkl/#respond Thu, 27 Aug 2026 22:38:31 +0000 https://www.laboratorynotes.com/?p=30071 MLKL is the terminal effector of necroptosis. After phosphorylation by RIPK3, MLKL oligomerises and inserts into the plasma membrane, causing membrane rupture and release of inflammatory DAMPs. MLKL is essential for regulated necrotic cell death and immune activation.

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]]> https://www.laboratorynotes.com/mlkl/feed/ 0 Immune System https://www.laboratorynotes.com/immune-system/ https://www.laboratorynotes.com/immune-system/#respond Tue, 29 Jul 2025 16:42:22 +0000 https://www.laboratorynotes.com/?p=22456 The immune system is the body’s defense network against infections and harmful substances. Learn about its major components, immune cells, types of immunity, antibodies, inflammation, and immune memory.

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]]> https://www.laboratorynotes.com/immune-system/feed/ 0 Tryptophan https://www.laboratorynotes.com/tryptophan/ https://www.laboratorynotes.com/tryptophan/#respond Tue, 13 May 2025 10:46:31 +0000 https://www.laboratorynotes.com/?p=19039 Tryptophan is an essential amino acid with important roles in protein synthesis, neurotransmitter production, immune regulation, and metabolism. It serves as a precursor for serotonin and melatonin and is also metabolized through the kynurenine pathway to produce several biologically active compounds.

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