Intron retention Archives - Laboratory Notes https://www.laboratorynotes.com/tag/intron-retention/ Tue, 15 Sep 2026 00:25:00 +0000 en hourly 1 https://wordpress.org/?v=7.1 Splice-Site Mutation https://www.laboratorynotes.com/splice-site-mutation/ https://www.laboratorynotes.com/splice-site-mutation/#respond Tue, 15 Sep 2026 00:23:21 +0000 https://www.laboratorynotes.com/?p=31258 Splice-site mutations are genetic variants that disrupt the signals required for accurate RNA splicing. They can cause exon skipping, intron retention, cryptic splice-site activation, abnormal mRNA production, and changes in protein expression.

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]]> https://www.laboratorynotes.com/splice-site-mutation/feed/ 0 Alternative 5′ and 3′ Splice Site https://www.laboratorynotes.com/alternative-5%e2%80%b2-and-3%e2%80%b2-splice-site/ https://www.laboratorynotes.com/alternative-5%e2%80%b2-and-3%e2%80%b2-splice-site/#respond Tue, 15 Sep 2026 00:05:11 +0000 https://www.laboratorynotes.com/?p=31250 Alternative 5′ and 3′ splice sites allow cells to select different boundaries during RNA splicing, producing mature RNA transcripts with different structures. Learn how spliceosomes, splicing factors, and regulatory sequences control alternative splice-site selection and influence gene expression.

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