Membrane trafficking Archives - Laboratory Notes https://www.laboratorynotes.com/tag/membrane-trafficking/ Fri, 21 Aug 2026 09:51:17 +0000 en hourly 1 https://wordpress.org/?v=7.1 RNF115 (RING Finger Protein 115) https://www.laboratorynotes.com/rnf115-ring-finger-protein-115/ https://www.laboratorynotes.com/rnf115-ring-finger-protein-115/#respond Fri, 21 Aug 2026 09:51:17 +0000 https://www.laboratorynotes.com/?p=29796 RNF115 (BCA2) is a dual RING/U‑box E3 ubiquitin ligase that regulates membrane trafficking, innate immunity and antiviral defence. By ubiquitinating BST‑2/Tetherin, Rab7‑associated endosomal proteins and EGFR, RNF115 influences receptor turnover, immune signalling and cancer progression, making it a key regulator of cellular homeostasis.

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]]> https://www.laboratorynotes.com/rnf115-ring-finger-protein-115/feed/ 0 Membrane Trafficking https://www.laboratorynotes.com/membrane-trafficking/ https://www.laboratorynotes.com/membrane-trafficking/#respond Mon, 21 Apr 2025 07:55:10 +0000 https://www.laboratorynotes.com/?p=17932 Membrane trafficking is the vesicular transport system that moves proteins and lipids between organelles, enabling secretion, endocytosis and cellular signalling. Regulated by Rab GTPases, coat proteins and SNARE complexes, these pathways maintain organelle identity, nutrient uptake and membrane turnover, forming a central mechanism of eukaryotic cell organisation.

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