ML‑IAP Archives - Laboratory Notes https://www.laboratorynotes.com/tag/ml-iap/ Mon, 24 Aug 2026 08:27:12 +0000 en hourly 1 https://wordpress.org/?v=7.1 Livin (ML‑IAP) https://www.laboratorynotes.com/livin-ml-iap/ https://www.laboratorynotes.com/livin-ml-iap/#respond Mon, 24 Aug 2026 08:27:12 +0000 https://www.laboratorynotes.com/?p=29853 Livin (ML‑IAP) is a tumour‑specific inhibitor of apoptosis that blocks caspase activity and ubiquitinates pro‑apoptotic proteins. Its splice variants, Livin‑α and Livin‑β, differ in potency, and its unique ability to switch from anti‑apoptotic to pro‑apoptotic after cleavage makes Livin a key regulator of tumour survival and therapy resistance.

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