NAIP Archives - Laboratory Notes https://www.laboratorynotes.com/tag/naip/ Tue, 25 Aug 2026 06:52:39 +0000 en hourly 1 https://wordpress.org/?v=7.1.2 IAP Family https://www.laboratorynotes.com/iap-family/ https://www.laboratorynotes.com/iap-family/#respond Tue, 25 Aug 2026 06:52:39 +0000 https://www.laboratorynotes.com/?p=29840 The IAP family consists of intracellular proteins that regulate apoptosis, ubiquitination and immune signalling. Through their BIR domains and RING ligase activity, IAPs control caspase inhibition, NF‑κB activation, inflammasome signalling and tumour cell survival, making them central players in cell biology and cancer research.

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]]> https://www.laboratorynotes.com/iap-family/feed/ 0 NAIP https://www.laboratorynotes.com/naip/ https://www.laboratorynotes.com/naip/#respond Mon, 24 Aug 2026 08:35:31 +0000 https://www.laboratorynotes.com/?p=29855 NAIP is a pattern‑recognition receptor that detects bacterial ligands such as flagellin and type III secretion system proteins. By recruiting NLRC4 to form the NAIP–NLRC4 inflammasome, NAIP activates caspase‑1, triggers pyroptosis and drives early innate immune defence against intracellular pathogens.

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