Survivin Archives - Laboratory Notes https://www.laboratorynotes.com/tag/survivin/ Mon, 24 Aug 2026 08:48:11 +0000 en hourly 1 https://wordpress.org/?v=7.1 Chromosomal Passenger Complex https://www.laboratorynotes.com/chromosomal-passenger-complex/ https://www.laboratorynotes.com/chromosomal-passenger-complex/#respond Mon, 24 Aug 2026 08:48:11 +0000 https://www.laboratorynotes.com/?p=29860 The Chromosomal Passenger Complex (CPC) is a dynamic mitotic regulator composed of Aurora B, INCENP, Borealin and Survivin. It ensures accurate chromosome segregation, corrects spindle attachment errors and coordinates cytokinesis, making it essential for genomic stability and highly relevant in cancer biology.

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]]> https://www.laboratorynotes.com/chromosomal-passenger-complex/feed/ 0 Survivin https://www.laboratorynotes.com/survivin/ https://www.laboratorynotes.com/survivin/#respond Mon, 24 Aug 2026 08:41:30 +0000 https://www.laboratorynotes.com/?p=29858 Survivin (BIRC5) is a tumour‑specific IAP that integrates apoptosis suppression with essential mitotic functions. As part of the chromosomal passenger complex, Survivin ensures proper chromosome segregation while stabilising anti‑apoptotic pathways, making it a central driver of tumour progression and therapy resistance.

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