Category: Database: Enzyme

Type I Topoisomerase

Type I topoisomerases are enzymes responsible for regulating DNA topology by relaxing supercoiled DNA. Unlike type II topoisomerases, which cleave…

Type II Topoisomerase

Type II topoisomerases are essential enzymes responsible for managing DNA topology in both prokaryotic and eukaryotic cells.  They play a…

Topoisomerase IV

Topoisomerase IV is a bacterial enzyme that plays a crucial role in DNA replication and chromosome segregation.  As a type…

DNA Gyrase

DNA gyrase is an essential bacterial enzyme that introduces negative supercoiling into DNA, facilitating processes such as replication, transcription, and…

SARS-CoV-2 RNA Polymerase

SARS-CoV-2 RNA polymerase, also known as RNA-dependent RNA polymerase (RdRp) or nonstructural protein 12 (nsp12), is a crucial viral enzyme…

Qβ Replicase

Qβ replicase is a viral RNA-dependent RNA polymerase (RdRp) found in bacteriophage Qβ, a positive-sense single-stranded RNA virus that infects…

Ribonuclease P (RNase P)

Ribonuclease P (RNase P) is an essential ribonucleoprotein enzyme involved in the maturation of transfer RNA (tRNA) molecules. Its primary…

Ribonuclease L (RNase L) 

RNase L is an interferon-induced endoribonuclease that plays a key role in the mammalian innate immune response, particularly in antiviral…

Ribonuclease R (RNase R)

Ribonuclease R (RNase R) is a 3′ to 5′ exoribonuclease that plays a crucial role in RNA metabolism, particularly in…

Telomerase

Telomerase is a specialized ribonucleoprotein reverse transcriptase that plays a critical role in maintaining telomere length at the ends of…

DNA Polymerase β

DNA Polymerase β (Pol β) is a DNA-dependent DNA polymerase primarily involved in base excision repair (BER) in eukaryotic cells….

DNA Polymerase III

DNA Polymerase III is the primary enzyme responsible for chromosomal DNA replication in Escherichia coli and other prokaryotes. As a…

DNA Polymerase I

DNA Polymerase I is a DNA-dependent DNA polymerase first discovered in Escherichia coli by Arthur Kornberg in 1956.  It was…

DNA-dependent DNA Polymerase

DNA-dependent DNA polymerases are enzymes that catalyze the synthesis of a new DNA strand using an existing DNA template.  They…

Polymerase

Polymerases are a fundamental class of enzymes responsible for synthesizing DNA and RNA molecules by forming phosphodiester bonds between nucleotides. …