Recent Posts

NPM -/- Mouse Embryonic Fibroblasts

Express relatively high level of p53 and p21 Undergo senescence (early passage cells) Post-mitotic tetraploid cell-cycle arrest and polyploidy Aberrant…

Nucleophosmin Knockout Mouse

Embryonic lethal, die between E11.5 and E12.5 (Grisendi et al., 2005)

qPCR Primers for β-Actin

qPCR primers for Mouse β-Actin Source: Li et al., 2008. supplementary information Forward Primer: 5’-GCTGTGCTATGTTGCTCTAG-3’ Reverse Primer:  5’-CGCTCGTTGCCAATAGTG-3’ #

qPCR Primers for ELF1a

qPCR primers for Mouse ELF1a Source: Li et al., 2008. supplementary information Forward Primer: 5’-AAAATTGGCTACAACCCCGA-3’ Reverse Primer:  5’-CCAACCAGAAATTGGCACAA-3’ #

qPCR Primers for Mouse GAS1

qPCR primers for Mouse GAS1 Source: Li et al., 2008. supplementary information Forward Primer: 5’-TCCCCTTACCGATTCATTCCT-3’ Reverse Primer:  5’-CAATCGCCAGCTCCACACT-3’ #

qPCR Primers for EIF4E

qPCR primers for Mouse EIF4E Source: Li et al., 2008. supplementary information Forward Primer: 5’-GGACGGGATTGAGCCTATGTG-3’ Reverse Primer:  5’-CAGCAGTGTCTCTAGCCAGAAG-3’ #

qPCR Primers for CDK4

CDK4 primers for Mouse Nucleolin Source: Li et al., 2008. supplementary information Forward Primer: 5’-GCAGTCTACATACGCAACAC-3’ Reverse Primer:  5’-TCGTCTTCTGGAGGCAATC-3’ #

qPCR Primers for Nucleolin

qPCR primers for Mouse Nucleolin Source: Li et al., 2008. supplementary information Forward Primer: 5′-ACACCAGCCAAAGTCATTCC-3′ Reverse Primer:  5′-ATCCTCATCACTGTCTTCCTTC-3′ #

Nucleophosmin and c-Myc Interaction

NPM is important for the oncogenic functions of c-Myc. Its overexpression enhances the hyperproliferation and transformation driven by c-Myc, while…

Nucleophosmin in Cell Transformation

Nucleophosmin (NPM) plays a significant role in cell transformation, particularly through its interaction with c-Myc. In their 2008 study, Li…

Nucleophosmin (NPM) in Cell Proliferation

Note: The protein nucleophosmin is commonly referred to as NPM or NPM1 in the literature. Nucleophosmin can enhance cell proliferation. …

Nucleolus

The nucleolus is the most prominent membrane-less subnuclear structure found in all eukaryotic cells during interphase, although it disappears during…

Nucleophosmin (NPM) in Nucleolus

Note: The protein nucleophosmin is commonly referred to as NPM or NPM1 in the literature. The protein Nucleophosmin is primarily…

Nucleophosmin (NPM)

Synonyms: Nucleophosmin/B23 Nucleophosmin Numatrin B23 NPM NPM1 NO38 Note: NPM1 is commonly referred to as nucleophosmin, while other nucleophosmins like…

ORC1

Large subunit of Origin Recognition Complex (ORC) Play role in initiation of replication of genomic DNA In humans, ORC1 is…