Author: admin

Evolutionary Insights from the Nucleolar Proteome

The nucleolus, once regarded merely as a static structure dedicated to ribosome production, is now recognized as a dynamic and…

Nucleolar Proteome

The nucleolar proteome refers to the full array of proteins present in the nucleolus, a dense, membrane-less structure within the…

European Medicines Agency (EMA)

The European Medicines Agency (EMA) is a decentralized agency of the European Union (EU) responsible for the scientific evaluation, supervision,…

U.S. Food and Drug Administration (FDA)

The U.S. Food and Drug Administration (FDA) is a federal agency within the U.S. Department of Health and Human Services…

ALCOA Principles

The ALCOA principles are fundamental concepts used to ensure the integrity, reliability, and trustworthiness of data, particularly in regulated environments…

Pharmaceutical Quality System

A Pharmaceutical Quality System (PQS) is a comprehensive framework designed to ensure that pharmaceutical products are consistently produced and controlled…

Topic: Good Manufacturing Practice (GMP)

Good Manufacturing Practice (GMP)   ALCOA Principles   Pharmaceutical Quality System Quality Control (QC) Methods for Advanced Therapy Medicinal Products (ATMPs) ISO…

ISO 9000 family

The ISO 9000 family is a set of international standards developed by the International Organization for Standardization (ISO) that provides…

Proton Sponge Effect

The proton sponge effect is a widely accepted mechanism that explains how certain cationic polymers, particularly polyethyleneimine (PEI), enhance gene…

Topic: Polyethyleneimine

Polyethyleneimine   ChemDB: Polyethyleneimine Polyethyleneimine in Nanotechnology   Polyethyleneimine as a Transfection Reagent: Enabling Efficient Gene Delivery in Mammalian Cells

Polyethyleneimine in Nanotechnology

Polyethyleneimine (PEI) plays a significant and multifaceted role in the field of nanotechnology, owing to its unique physicochemical properties.  As…

Polyethyleneimine as a Transfection Reagent: Enabling Efficient Gene Delivery in Mammalian Cells

Polyethyleneimine (PEI) is a synthetic cationic polymer that has become a widely used non-viral vector for gene delivery in eukaryotic…

Polyethyleneimine

Polyethyleneimine (PEI) is a synthetic polymer composed of repeating ethyleneimine units (–CH₂CH₂NH–) that exhibits a high density of amine groups,…

ChemDB: Polyethyleneimine

Composition: Synthetic polymer with repeating ethyleneimine units (‑CH₂CH₂NH‑) Forms: Branched PEI (25%, 50%, 75% branching) Linear PEI (LPEI) (near 100%…

Topic: Transfection

Transfection Transfection: Timeline of Key Events   Large-Scale Transient Transfection of Mammalian Suspension Cells for Rapid Protein Production