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The Boveri–Sutton chromosome theory states that chromosomes are the carriers of genetic material and play a crucial role in heredity. …

CagA (Cytotoxin-Associated Gene A) CagA/E-cadherin interaction ExpSup: CagA Induces P21 Expression ExpSup: CagA Induces β-catenin Relocalization from Cell Membrane to…

Note: For more detailed and accurate information, please read the cited reference. Overexpressed Pragmin is localized to cytoplasm in the…

Note: For more detailed and accurate information, please read the cited reference. Pragmin overexpression induces morphological changes in AGS cells,…

Note: For more detailed and accurate information, please read the cited reference. Pragmin overexpression causes morphological changes in AGS cell…

Note: For more detailed and accurate information, please read the cited reference. Overexpression of Pragmin in the AGS cell line…

Vector type: Mammalian expression plasmid vector Based on: high-copy-number pUC plasmid vector Bacterial system: Selection: Kanamycin (Kanamycin-resistance gene under control…

Synonym:  Pragmin SgK223 Subcellular localization: Cytoplasm Pseudokinase Contain EPIYA-moitif Tyrosine phosphorylation at the EPIYA motif by SFKs (Safari et al.,…

Express relatively high level of p53 and p21 Undergo senescence (early passage cells) Post-mitotic tetraploid cell-cycle arrest and polyploidy Aberrant…

Embryonic lethal, die between E11.5 and E12.5 (Grisendi et al., 2005)

qPCR primers for Mouse β-Actin Source: Li et al., 2008. supplementary information Forward Primer: 5’-GCTGTGCTATGTTGCTCTAG-3’ Reverse Primer:  5’-CGCTCGTTGCCAATAGTG-3’ #

qPCR primers for Mouse ELF1a Source: Li et al., 2008. supplementary information Forward Primer: 5’-AAAATTGGCTACAACCCCGA-3’ Reverse Primer:  5’-CCAACCAGAAATTGGCACAA-3’ #

qPCR primers for Mouse GAS1 Source: Li et al., 2008. supplementary information Forward Primer: 5’-TCCCCTTACCGATTCATTCCT-3’ Reverse Primer:  5’-CAATCGCCAGCTCCACACT-3’ #

qPCR primers for Mouse EIF4E Source: Li et al., 2008. supplementary information Forward Primer: 5’-GGACGGGATTGAGCCTATGTG-3’ Reverse Primer:  5’-CAGCAGTGTCTCTAGCCAGAAG-3’ #

CDK4 primers for Mouse Nucleolin Source: Li et al., 2008. supplementary information Forward Primer: 5’-GCAGTCTACATACGCAACAC-3’ Reverse Primer:  5’-TCGTCTTCTGGAGGCAATC-3’ #