Category: Lab Notes: Immunology

Human Leukocyte Antigen (HLA)/Major Histocompatibility Complex (MHC)

Human Leukocyte Antigen (HLA), also known as the Major Histocompatibility Complex (MHC) in humans, is a complex gene system crucial…

Interferon

Interferons (IFNs) are a family of cytokines that play crucial roles in the immune response, particularly against viral infections. They…

Interleukin

Interleukins (ILs) are a large family of cytokines that play essential roles in the immune system, mediating communication between leukocytes…

T Cell Receptor (TCR)

The T cell receptor (TCR) is a specialized molecular complex found on the surface of T lymphocytes that enables these…

Polyclonal Antibodies Vs Monoclonal Antibodies

Criteria Polyclonal Antibodies Monoclonal Antibodies Remarks Definition A heterogeneous mixture of antibodies produced by multiple B-cell clones Homogeneous antibodies derived…

Phagocytosis

Phagocytosis is a fundamental cellular process where specialized cells engulf and destroy particles, pathogens, and dead cells. This process is…

Antigen

An antigen is any substance that can trigger an immune response and be specifically recognized by the immune system. These…

Innate Immunity Vs Adaptive Immunity

Criteria Innate Immunity Adaptive Immunity Remarks Definition First line of defense with non-specific response Second line of defense with antigen-specific…

Hypersensitivity

Hypersensitivity reactions are excessive or inappropriate immune responses that can damage tissues and cause disease. These reactions are classified into…

Adaptive Immunity

Adaptive immunity is a highly specific defense system that develops throughout our lifetime in response to exposure to pathogens and…

Innate Immunity

Innate immunity represents the body’s first line of defense against pathogens, consisting of both physical barriers and cellular responses that…

Platelets

Platelets, also known as thrombocytes, are small anucleate blood cells essential for hemostasis, wound healing, and various immune responses. These…

Red Blood Cells (RBCs)

Red blood cells (RBCs), or erythrocytes, are highly specialized cells dedicated to oxygen transport throughout the body. These unique cells,…

Hematopoietic Stem Cells (HSCs)

Hematopoietic stem cells (HSCs) are rare, self-renewing cells residing primarily in the bone marrow that give rise to all blood…

Mucosal Immunity 

Mucosal immunity is a crucial component of the immune system that provides protection at mucosal surfaces, which are the primary…