Tag: Antibiotic resistance

Penicillin-binding proteins are essential bacterial enzymes involved in peptidoglycan synthesis and cell-wall cross-linking. Explore transpeptidation, D-alanine-containing precursors, β-lactam antibiotics and bacterial resistance mechanisms.

β-Lactam antibiotics target bacterial cell-wall synthesis by inhibiting penicillin-binding proteins and transpeptidation. Explore penicillins, cephalosporins, carbapenems, monobactams, β-lactamases and major bacterial resistance mechanisms.