Tag: DNA demethylation

DNA methylation is a major epigenetic mechanism that regulates gene expression and may contribute to transgenerational effects under specific biological conditions. Learn about DNA methylation, germ-cell reprogramming, DNA methyltransferases, imprinting, environmental influences, epimutations, and the challenges of demonstrating true transgenerational inheritance.

Intergenerational epigenetic effects describe how parental exposures and physiological conditions may influence gene regulation and biological traits in offspring. Learn about DNA methylation, histone modifications, germ-cell epigenetics, maternal and paternal effects, environmental influences, development, and the distinction from transgenerational inheritance.

Epigenetic reprogramming in germ cells resets and establishes gene-regulatory patterns during the formation of eggs and sperm. Learn about DNA methylation, histone modifications, chromatin remodeling, genomic imprinting, X-chromosome regulation, epigenetic inheritance, and reproductive genetics.

Epigenetic reprogramming resets and establishes gene-regulatory states through changes in DNA methylation, histone modifications, chromatin structure, and other epigenetic mechanisms. Learn about its role in germ cells, embryonic development, stem cells, inheritance, aging, cancer, and human genetics.