EZH2 is the major catalytic methyltransferase component of PRC2 and plays a central role in Polycomb-mediated gene regulation. Learn how EZH2 establishes H3K27 methylation and contributes to development, stem-cell regulation, epigenetic memory, and cancer.
H3K27me3 is a major epigenetic histone modification associated with Polycomb-mediated gene repression. Established primarily by PRC2, it plays important roles in chromatin regulation, development, stem-cell biology, cellular differentiation, and disease.
EZH2 is the major catalytic methyltransferase component of PRC2 and plays a central role in Polycomb-mediated gene regulation. Learn how EZH2 establishes H3K27 methylation and contributes to development, stem-cell regulation, epigenetic memory, and cancer.
H3K27me3 is a major epigenetic histone modification associated with Polycomb-mediated gene repression. Established primarily by PRC2, it plays important roles in chromatin regulation, development, stem-cell biology, cellular differentiation, and disease.
