H2AK119ub is a major histone modification associated with PRC1-mediated Polycomb repression. Established primarily by RING1A and RING1B, it contributes to chromatin organization, transcriptional repression, development, stem-cell regulation, and cellular identity.
H2AK119ub is a major histone modification associated with PRC1-mediated Polycomb repression. Established primarily by RING1A and RING1B, it contributes to chromatin organization, transcriptional repression, development, stem-cell regulation, and cellular identity.
