Tag: NR5A1
Sertoli Cell‑Only Syndrome
Sertoli‑cell‑only syndrome is a severe testicular disorder in which seminiferous tubules contain only Sertoli cells and no germ cells. Caused by AZFa microdeletions, germ‑cell developmental gene mutations or acquired testicular injury, SCOS represents an advanced form of non‑obstructive azoospermia with major implications for fertility and genetic counselling.
Sertoli Cell‑Only Syndrome
Sertoli‑cell‑only syndrome is a severe testicular disorder in which seminiferous tubules contain only Sertoli cells and no germ cells. Caused by AZFa microdeletions, germ‑cell developmental gene mutations or acquired testicular injury, SCOS represents an advanced form of non‑obstructive azoospermia with major implications for fertility and genetic counselling.