RING E3 ligase oligomerization enables the formation of dimers, multimers, and higher-order complexes that regulate E2 recruitment, substrate recognition, ubiquitin transfer, autoubiquitination, and cellular signaling.
RING E3 ligase regulation involves phosphorylation, ubiquitination, protein interactions, oligomerization, cellular localization, and signaling pathways that control E3 activity and substrate specificity.
RING E3 ligase oligomerization enables the formation of dimers, multimers, and higher-order complexes that regulate E2 recruitment, substrate recognition, ubiquitin transfer, autoubiquitination, and cellular signaling.
RING E3 ligase regulation involves phosphorylation, ubiquitination, protein interactions, oligomerization, cellular localization, and signaling pathways that control E3 activity and substrate specificity.
