Tag: Polycomb proteins

PRC1 and PRC2 are major Polycomb Repressive Complexes that regulate gene expression through chromatin modification and organization. They play essential roles in development, differentiation, stem-cell biology, cellular identity, and epigenetic gene regulation.

Polycomb-group proteins are conserved chromatin-associated regulators that control gene expression through epigenetic mechanisms. They function primarily through Polycomb Repressive Complexes such as PRC1 and PRC2 and play important roles in development, cellular differentiation, stem-cell biology, chromatin organization, and cancer.