Tag: Post-translational modifications

Protein phosphorylation is a reversible post-translational modification that regulates protein activity, stability, localization, interactions, and cellular signaling. Learn about protein kinases, phosphatases, phosphorylation sites, signaling pathways, phosphoproteomics, disease mechanisms, and therapeutic applications.

Post-translational modifications (PTMs) are biochemical changes that occur during or after protein synthesis and regulate protein structure, activity, stability, localization, interactions, and degradation. This overview introduces the major types of PTMs, their biological functions, mechanisms, role in disease, and methods used to study protein modifications.