The heat‑shock response (HSR) is a conserved cellular defence pathway that protects the proteome under stress. By activating HSF1 and inducing heat‑shock proteins, cells stabilise protein folding, prevent aggregation and restore proteostasis during proteotoxic conditions.
The heat‑shock response (HSR) is a conserved cellular defence pathway that protects the proteome under stress. By activating HSF1 and inducing heat‑shock proteins, cells stabilise protein folding, prevent aggregation and restore proteostasis during proteotoxic conditions.
