Tag: Protein regulation

Protein succinylation is a metabolic post-translational modification that connects succinyl-CoA metabolism with protein function, mitochondrial activity, epigenetic regulation, gene expression and cellular homeostasis.

Lysine malonylation is a metabolic post-translational modification that connects malonyl-CoA metabolism with protein function, mitochondrial activity, epigenetic regulation and cellular homeostasis.

Post-translational modifications (PTMs) are biochemical changes that occur during or after protein synthesis and regulate protein structure, activity, stability, localization, interactions, and degradation. This overview introduces the major types of PTMs, their biological functions, mechanisms, role in disease, and methods used to study protein modifications.