Tag: Pyroptosis
Programmed Cell Death
Programmed cell death (PCD) is a regulated biological process that eliminates damaged or unnecessary cells through apoptosis, autophagic cell death and regulated necrosis. By maintaining tissue homeostasis and supporting stress adaptation, PCD is essential for development and long‑term organismal health.
NAIP
NAIP is a pattern‑recognition receptor that detects bacterial ligands such as flagellin and type III secretion system proteins. By recruiting NLRC4 to form the NAIP–NLRC4 inflammasome, NAIP activates caspase‑1, triggers pyroptosis and drives early innate immune defence against intracellular pathogens.
Programmed Cell Death
Programmed cell death (PCD) is a regulated biological process that eliminates damaged or unnecessary cells through apoptosis, autophagic cell death and regulated necrosis. By maintaining tissue homeostasis and supporting stress adaptation, PCD is essential for development and long‑term organismal health.
NAIP
NAIP is a pattern‑recognition receptor that detects bacterial ligands such as flagellin and type III secretion system proteins. By recruiting NLRC4 to form the NAIP–NLRC4 inflammasome, NAIP activates caspase‑1, triggers pyroptosis and drives early innate immune defence against intracellular pathogens.