Tag: Pyroptosis
NAIP
NAIP is a pattern‑recognition receptor that detects bacterial ligands such as flagellin and type III secretion system proteins. By recruiting NLRC4 to form the NAIP–NLRC4 inflammasome, NAIP activates caspase‑1, triggers pyroptosis and drives early innate immune defence against intracellular pathogens.
NAIP
NAIP is a pattern‑recognition receptor that detects bacterial ligands such as flagellin and type III secretion system proteins. By recruiting NLRC4 to form the NAIP–NLRC4 inflammasome, NAIP activates caspase‑1, triggers pyroptosis and drives early innate immune defence against intracellular pathogens.