Necroptosis is a regulated necrotic cell‑death pathway driven by RIPK1–RIPK3–MLKL signalling. Through membrane permeabilisation and inflammatory activation, necroptosis eliminates infected or damaged cells when apoptosis is blocked, shaping immunity and disease progression.
Necroptosis is a regulated necrotic cell‑death pathway driven by RIPK1–RIPK3–MLKL signalling. Through membrane permeabilisation and inflammatory activation, necroptosis eliminates infected or damaged cells when apoptosis is blocked, shaping immunity and disease progression.
