RING1A and RING1B are key E3 ubiquitin ligases within PRC1 that establish H2AK119ub, an important Polycomb-associated histone modification. Discover how these proteins regulate chromatin, gene repression, development, stem cells, and cellular identity.
RING1A and RING1B are key E3 ubiquitin ligases within PRC1 that establish H2AK119ub, an important Polycomb-associated histone modification. Discover how these proteins regulate chromatin, gene repression, development, stem cells, and cellular identity.
