Tag: TRIM25
TRIM25
TRIM25 is a RING finger ubiquitin ligase that activates the antiviral sensor RIG‑I through K63‑linked ubiquitination. Its tripartite motif and PRY/SPRY domain enable precise regulation of innate immune signalling, interferon production and viral restriction. TRIM25 is targeted by multiple viruses, highlighting its importance as a frontline antiviral factor.
TRIM25
TRIM25 is a RING finger ubiquitin ligase that activates the antiviral sensor RIG‑I through K63‑linked ubiquitination. Its tripartite motif and PRY/SPRY domain enable precise regulation of innate immune signalling, interferon production and viral restriction. TRIM25 is targeted by multiple viruses, highlighting its importance as a frontline antiviral factor.