Binding Strength of Protein A/G to Mouse Immunoglobulins

The following Table compares the relative affinity of Protein A and Protein G for Mouse immunoglobulins (antibodies).

Immunoglobulin type and classProtein A bindingProtein G binding
IgG1++++
IgG2a++++++
IgG2b++++
IgG3+++++
IgM*+++/–
IgA++++++

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