SYCP1 is a meiosis‑specific protein that forms the transverse filaments of the synaptonemal complex. Its correct assembly is essential for homologous chromosome pairing, recombination, and fertility.
SYCP3 is a meiosis‑specific protein essential for chromosomal synapsis and the formation of the synaptonemal complex. Mutations in SYCP3 are linked to meiotic arrest, infertility, and genomic instability.
The synaptonemal complex is a meiosis‑specific protein structure essential for homologous chromosome pairing, recombination, and fertility. Its disruption leads to meiotic arrest, aneuploidy, and reproductive disorders.
Shelterin is a protein complex that protects telomeres and maintains chromosome stability. This article explains its structure, components, and essential role in telomere regulation and DNA damage prevention.
