Category: Database: Gene/Protein
Histone H4
Histone H4 is one of the four core histone proteins—along with H2A, H2B, and H3—that form the fundamental unit of…
Histone H3
Histone H3 stands as one of the most fundamental and highly conserved proteins in eukaryotic organisms, playing a central role…
Histone H2A
Histone H2A represents one of the core histone proteins that play a fundamental role in chromatin organization and regulation within…
Histone H2B
Histone H2B is one of the core histone proteins that play a fundamental role in chromatin organization and regulation of…
Caspase-4
Caspase-4 is an inflammatory caspase primarily involved in the innate immune response and inflammatory cell death (pyroptosis). Unlike executioner caspases,…
Caspase-1
Caspase-1, also known as interleukin-1β converting enzyme (ICE), is a critical inflammatory caspase that plays a central role in innate…
Caspase-3
Caspase-3 is a crucial executioner caspase that plays a central role in the implementation phase of apoptosis. As one of…
Caspase-10
Caspase-10 is a member of the cysteine-aspartic acid protease (caspase) family that plays a crucial role in the initiation of…
Caspase-8
Caspase-8 is a crucial initiator caspase that plays a central role in the extrinsic apoptotic pathway and serves as a…
Caspase-2
Caspase-2 is one of the most evolutionarily conserved members of the caspase family and possesses unique characteristics that set it…
Caspase
Caspases (Cysteine-dependent aspartate-directed proteases) are a family of enzymes that play crucial roles in programmed cell death (apoptosis) and inflammation….
BAK1 (BCL2 Antagonist/Killer 1)
BAK1 (BCL2 Antagonist/Killer 1) is a pro-apoptotic member of the BCL-2 protein family that plays a crucial role in programmed…
BAX (Bcl-2-Associated X Protein)
BAX (Bcl-2-associated X protein) is a pro-apoptotic member of the BCL-2 protein family that plays a central role in programmed…
Regulation of SHP-2 by Calpeptin
SHP-2 (Src homology region 2 domain-containing phosphatase-2) is a non-receptor protein tyrosine phosphatase encoded by the PTPN11 gene. It plays…
Calpeptin
Calpeptin is a cell-permeable synthetic peptide inhibitor that specifically targets calpains, which are calcium-dependent cysteine proteases. This compound has become…