- The GeoMx™ Digital Spatial Profiler (DSP) is an advanced spatial biology platform developed by NanoString Technologies, designed for high-throughput spatial transcriptomics and proteomics.
- It enables researchers to analyze the molecular composition of tissues with high spatial resolution, preserving cellular and tissue context while providing quantitative gene and protein expression data.
- This technology is particularly useful for studying heterogeneous tissues, such as tumors, brain tissue, and immune environments, where spatial organization plays a crucial role in biological function and disease progression.
- One of the key strengths of GeoMx DSP is its region-of-interest (ROI) selection capability, allowing researchers to precisely target specific areas within a tissue sample for molecular profiling.
- Using UV-photocleavable barcoded oligonucleotides, the system enables the multiplexed detection of RNA and proteins without disrupting tissue integrity.
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