Posted in Database: Gene/ProteinNPM -/- Mouse Embryonic Fibroblasts admin December 5, 2024 Leave a Comment on NPM -/- Mouse Embryonic FibroblastsExpress relatively high level of p53 and p21 Undergo senescence (early passage cells)Post-mitotic tetraploid cell-cycle arrest and polyploidyAberrant mitotic figures with multiple centrosomes and multipolar spindles Author: admin