Several mycoplasma species from human, porcine and bovine origin have been detected in cell culture. The following eight species account for 95% cell culture contamination.
| Species | Origin | Surces |
| Mycoplasma fermentans | human | Human generated aerosol |
| Mycoplasma hominis | human | Human generated aerosol |
| Mycoplasma orale | human | Human generated aerosol |
| Mycoplasma pirum | human | Human generated aerosol |
| Mycoplasma salivarium | human | Human generated aerosol |
| Mycoplasma hyorhinis | porcine | Trypsin solution |
| Mycoplasma arginini | bovine | bovine serum |
| Acholeplasma laidlawii | bovine | bovine serum |
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