Category: Lab Notes

Controlled‑Rate Freezing Container

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Controlled‑rate freezing containers provide reproducible cooling rates for cryopreservation using standard −80 °C freezers. This article explains their principles, applications, major brands, and specialised features.

Personal Protective Equipment

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Personal Protective Equipment (PPE) protects individuals from chemical, biological, and physical hazards in laboratories and industrial environments. This article explains its importance, types, major brands, and specialised features.

Hemocytometer

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The hemocytometer is a precision‑etched glass slide used for manual cell counting and viability assessment. This article explains its design, principle, applications, major brands, and special features.

Ubiquitylation

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Ubiquitylation is a post‑translational modification that regulates protein stability, activity, and signalling. This article explains its mechanisms, types, functions, and roles in health and disease.

Ubiquitin–Proteasome System in Immune Cells

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The ubiquitin–proteasome system regulates immune cell function by controlling protein turnover, antigen presentation, and signalling. This article explains its mechanisms and roles in innate and adaptive immunity.

Ubiquitin–Proteasome System in Cellular Regulation

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The ubiquitin–proteasome system is the major pathway for selective protein degradation and cellular regulation. This article explains its mechanisms, regulatory roles, and significance in health and disease.

Proteome

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The proteome is the complete set of proteins expressed by a cell or organism. This article explains its dynamic nature, regulation, analytical methods, and importance in health and disease.

Proteostasis

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Proteostasis is the cellular system that maintains protein quality through folding, repair, and degradation. This article explains its components, stress responses, and roles in ageing and disease.

Cyclin

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Cyclins are regulatory proteins that control cell‑cycle progression by activating cyclin‑dependent kinases. This article explains their classes, functions, regulation, and roles in health and disease.

Deubiquitinating Enzyme

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Deubiquitinating enzymes (DUBs) are proteases that remove ubiquitin from proteins, regulating stability, activity, and cellular signalling. This article explains their families, functions, and roles in health and disease.

Serial Subculture for Maintenance of Microbial Cultures 

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Serial subculture is a key microbiological technique used to maintain viable, pure microbial cultures over time. This article explains its purpose, procedure, and importance in laboratory practice.

Nucleoid

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The nucleoid is the DNA‑containing region of prokaryotic cells, organised without a surrounding membrane. This article explains its structure, organisation, and essential role in gene expression and replication.

Disposal of Biohazardous Waste

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Biohazardous waste disposal is essential for laboratory safety and environmental protection. This article explains the types of biohazard waste, proper segregation, decontamination, and best practices for safe handling.

Origin of the Term “Cell”: A Historical Perspective

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The term cell is fundamental to modern biology, yet its origin lies in a simple visual observation made more than…