Category: Lab Notes: Biotechniques
Proteomics
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Proteomics is a rapidly evolving field of molecular biology dedicated to the large-scale study of proteins, the functional molecules that…
Transcriptomics
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Transcriptomics is a fundamental branch of molecular biology dedicated to studying the complete set of RNA transcripts produced by the…
Omics Technologies
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Omics technologies represent a revolutionary approach in modern biological research, enabling scientists to study living systems at an unprecedented molecular…
Spatial Omics Technologies
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Spatial omics technologies represent a revolutionary approach to studying biological systems by preserving the spatial organization of biomolecules such as…
Gravity Battery
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A gravity battery is an energy storage device that harnesses the force of gravity to store and release energy. The…
Spatial Multi-Omics
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Spatial multi-omics represents a revolutionary advancement in biological research, integrating multiple omics technologies within their native spatial context. This approach…
GeoMx Digital Spatial Profiler (DSP)
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The GeoMx™ Digital Spatial Profiler (DSP) is an advanced spatial biology platform developed by NanoString Technologies, designed for high-throughput spatial…
CosMx™ Spatial Molecular Imager (SMI)
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CosMx™ Spatial Molecular Imager (SMI) is an advanced single-cell imaging technology developed by NanoString Technologies, designed for high-resolution spatial transcriptomics…
Spatial Biology
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Spatial biology is a rapidly evolving field that aims to understand the organization and function of biological tissues and cells…
Cryoprotective Agent
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Cryoprotective agents (CPAs) protect biological materials during freezing and thawing by reducing ice formation, osmotic injury, and membrane damage. This article explains CPA types, mechanisms, toxicity, and their role in modern cryopreservation.
Applications of Cryopreservation
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Cryopreservation is a vital technology that preserves biological materials at ultra‑low temperatures, supporting medicine, research, agriculture, biotechnology, and wildlife conservation. This article explores its diverse applications and growing importance in science and global biodiversity protection.
Cryopreservation
Cryopreservation enables long‑term storage of living cells and tissues at ultra‑low temperatures by halting biological time. This article explains freezing damage, cryoprotective agents, slow freezing, vitrification, and natural freeze tolerance.
dCas9 (Endonuclease Dead Cas9)
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dCas9 is a mutated version of Cas 9 that lacks endonuclease activity (Endonuclease dead Cas9). It is created by point…
Targeting RNA using CRISPR-Cas
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The following CRISPR-Cas systems can be used to target and modify RNA in cells. The following Cas proteins can recognize…
Next-Generation Sequencing (NGS)
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Next-Generation Sequencing (NGS) refers to a suite of high-throughput DNA sequencing technologies that have revolutionized genomics by enabling rapid, cost-effective,…
