Methods to Visualize Blood Vessels in Brain

Anti-CD31 staining can be used to visualize blood vessels in different body parts including the brain.

Immunostaining of fixed brain slices using anti-CD31 (PECAM) antibodies is a powerful and easy way to visualize blood vessels in the brain. 

This method is used by Watkins et al., 2014  to study vascular co-option and perivascular invasion of glioma cells in the mouse brain.  


Watkins et al., 2014. Disruption of astrocyte-vascular coupling and the blood-brain barrier by invading glioma cells. Nat Commun. 5, 4196. PMID-24943270; Full Text Link: nature, PMC

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