Category: Experimetal Support

ExpSup: CagA Induces Cyclin D1 Expression

 admin  July 16, 2022  1 Comment on ExpSup: CagA Induces Cyclin D1 Expression

Murata-Kamiya et al., 2007 showed that cagA expression in MKN-28 cell line results in upregulation of cyclin D1 using western…

ExpSup: CagA Induces β-catenin Relocalization from Cell Membrane to Nucleus in Tyrosine-phosphorylation Independent Manner

 admin  July 15, 2022  0 Comments on ExpSup: CagA Induces β-catenin Relocalization from Cell Membrane to Nucleus in Tyrosine-phosphorylation Independent Manner

Murata-Kamiya et al., 2007 showed that β-catenin is localized in the plasma membrane at cell-cell junctions in the MKN-28 cell…

ExpSup: CagA Activates β-catenin in Tyrosine-phosphorylation Independent Manner

 admin  July 15, 2022  1 Comment on ExpSup: CagA Activates β-catenin in Tyrosine-phosphorylation Independent Manner

β-catenin is usually present in the plasma membrane at cell-cell junctions in a complex called adherens junction. Upon activation, β-catenin…

ExpSup: CagA Physically Interacts with E-cadherin in Tyrosine-phosphorylation Independent Manner

 admin  July 15, 2022  1 Comment on ExpSup: CagA Physically Interacts with E-cadherin in Tyrosine-phosphorylation Independent Manner

Murata-Kamiya et al., 2007 showed that E-cadherin physically interacts with CagA protein using co-immunoprecipitation in cell lysate prepared from MKN-28…

ExpSup: AGS Cell Line Does Not Express E-cadherin

 admin  July 10, 2022  0 Comments on ExpSup: AGS Cell Line Does Not Express E-cadherin

Hsieh et al., 1996 analyzed the surface expression of E-cadherin by flow cytometry in untreated cells and treated with TNFɑ,…

ExpSup: Hummingbird Phenotype is Induced only by CagA-positive Helicobacter pylori, but not by CagA-negative Helicobacter pylori

 admin  July 4, 2022  0 Comments on ExpSup: Hummingbird Phenotype is Induced only by CagA-positive Helicobacter pylori, but not by CagA-negative Helicobacter pylori

AGS cells acquire hummingbird phenotype when infected with CagA-positive H. pylori strain G27 but not with CagA-negative H. pylori strain…