Tag: Cell cycle and proliferation

Cyclin D

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D-type cyclins (or cyclin D)* are active in the G1 phase of the cell cycle. Their expression is induced by…

Restriction Point (R)

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Growth factor/mitogenic signaling is required for G1 phase progress. Withdrawal of growth factors/mitogens from cell culture can arrest the cells…

G1 phase

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The G1 phase begins with the generation of daughter cells following cytokinesis and ends when daughter cells are ready to…

G0 phase

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In some situations, proliferating cells stop cell division and exit the cell cycle in the G1 phase. These nonproliferative cells…