Tag: cell cycle and proliferation
Cyclin D
D-type cyclins (or cyclin D)* are active in the G1 phase of the cell cycle. Their expression is induced by…
Restriction Point (R)
Growth factor/mitogenic signaling is required for G1 phase progress. Withdrawal of growth factors/mitogens from cell culture can arrest the cells…
G1 phase
The G1 phase begins with the generation of daughter cells following cytokinesis and ends when daughter cells are ready to…
G0 phase
In some situations, proliferating cells stop cell division and exit the cell cycle in the G1 phase. These nonproliferative cells…