Preparation of 1M Potassium Chloride (KCl) Stock Solution


Potassium Chloride (KCl) dissolves readily in water. A 1 M stock solution can be prepared by dissolving 74.55 g KCL (Molecular Weight: 74.55) in water to a final volume of 1L. 

In the following section, we describe a procedure to prepare 100 ml of 1M KCl stock solution.


Reagents and solutions
Potassium chloride (KCl)
Deionized / Distilled water

Equipment and disposables
Measuring cylinder
Conical flask / Beaker

1 M Potassium chloride

Preparation of 100 ml 1 M Potassium chloride


Step 1: To prepare 100 ml of 1 M Potassium chloride, weigh out 7.455 g KCL (Molecular Weight: 74.55) in a 250 ml conical flask/beaker. Add 80 ml deionized/Milli-Q water and mix it. 

One can use manual shaking using a glass pipette to mix the ingredients. Magnetic stirrer makes the dissolving process easy and convenient.

Do not dissolve in 100 ml of deionized / Milli-Q water. In most cases, solution volume increases when a large amount of solute is dissolved in a solvent.

Step 2: Adjust the volume to 100 ml with deionized / Milli-Q water. Mix it again.

Step 3: Sterilize the solution by autoclaving (20 minutes at 15 lb/ (psi) from 121-124°C on liquid cycle).

The solution can be stored at room temperature or in a cold room.

Follow the table to prepare Potassium chloride of various concentrations and volumes (10, 100 ml, 500 ml, 1,000 ml, and 10,000 ml).
Solution concentration / Volume10 ml100 ml500 ml1000 ml
0.1 M0.075 g0.75 g3.73 g7.46 g
0.5 M0.37 g3.73 g18.64 g37.275 g
1 M0.75 g7.46 g37.275 g74.55 g

Was this post helpful?

Author: admin

1 thought on “Preparation of 1M Potassium Chloride (KCl) Stock Solution

  1. Preparation of KCL itself in a special container! Solution used! The rest, the precipitate of KCL that has not dissolved! Is it worth using it again?

Leave a Reply

Your email address will not be published. Required fields are marked *