References: PD98059

  • Karayiannis et al., 2023. Induction of MMP-3 and MMP-9 expression during Helicobacter pylori infection via MAPK signaling pathways. Helicobacter. 28(4), e12987. PMID-37139985; Full-Text Links: Wiley   
  • Lin et al., 2021. Terminal uridyltransferase 7 regulates TLR4-triggered inflammation by controlling Regnase-1 mRNA uridylation and degradation. Nat Commun. 12(1), 3878. PMID-34188032; Full-Text Links: Nature, PMC
  • Naguib et al., 2021. An injectable microparticle formulation for the sustained release of the specific MEK inhibitor PD98059: in vitro evaluation and pharmacokinetics. Drug Deliv Transl Res. 11(1), 182-191. PMID-32378175; Full-Text Links: Springer, PMC
  • Lee et al., 2009. Genetic reconstruction of mouse spermatogonial stem cell self-renewal in vitro by Ras-cyclin D2 activation. Cell Stem Cell. 5(1):76-86. PMID-19570516; Full-Text Link: Cell
  • Kojima et al., 2007. Mitogen-activated protein kinase kinase inhibition enhances nuclear proapoptotic function of p53 in acute myelogenous leukemia cells. Cancer Res. 67(7), 3210-9. PMID-17409429; Full-Text Links: aacrjournals 
  • Qi et al., 2004. BMP4 supports self-renewal of embryonic stem cells by inhibiting mitogen-activated protein kinase pathways. Proc Natl Acad Sci U S A. 101(16), 6027-32. PMID-15075392; Full-Text Links: PNAS, PMC395917 
  • Tsang et al., 1998. Effects of mitogen-activated protein kinase kinase inhibitor PD 098059 on antigen challenge of guinea-pig airways in vitro. Br J Pharmacol. 125(1), 61-8. PMID-9776345; Full-Text Links: Wiley, PMC1565601 
  • Alessi et al., 1995. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem. 270(46), 27489-94. PMID-7499206; Full-Text Link: JBC
  • Dudley et al., 1995. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc Natl Acad Sci U S A. 92(17), 7686-9. PMID-7644477; Full-Text Links: PNAS, PMC

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