List of Mammalian APC/C Substrates

  • Anillin 
  • Aurora kinase A 
  • Aurora kinase B 
  • Cyclin A2 
  • Cyclin B1 
  • Cell division cycle-associated protein 3 (Also known as Tome-1) 
  • Cell division cycle 6 homologue 
  • Cell division cycle protein 20 homologue 
  • Cell division cycle 25 homologue A 
  • p21 
  • Cytoskeleton associated protein 2 
  • Deoxythymidylate kinase 
  • Forkhead box M1 
  • Fizzy-related protein homologue (Cdh1) 
  • Geminin 
  • DNA-binding protein inhibitor ID-1 
  • DNA-binding protein inhibitor ID-2 
  • Kinesin family member 22 
  • Never in mitosis gene a-related protein kinase 2A 
  • Pfkfb3 
  • Polo-like kinase 1 
  • Securin (pituitary-tumour transforming gene1 protein)  
  • Regulator of chromosome segregation 
  • Shugoshin-like 1 
  • SKI-like oncogene (SnoN) 
  • S-phase kinase-associated protein 2 
  • Thymidine kinase 1 
  • Targeting protein for Xklp2 
  • Ubiquitin-conjugating enzyme E2 C (UbcH10)

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