- A diverse group of microorganisms that can utilize single carbon (C1) compounds such as methane, methanol, and methylamine, as a source of carbon and energy, are called Methylotroph.
- Phylogenetically very diverse group of microorganisms which span across the domains
- Include both Gram-positive and Gram-negative bacteria, and also yeasts
- Developed metabolic adaptations to utilize C1 compounds as an energy and carbon source
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