​​Adenovirus Mediated Gene Delivery to Mouse Liver Hepatocytes

A gene can be easily delivered using Adenovirus to the liver hepatocytes of mice. 

  • Nelsen and coworkers injected CsCl-purified adenoviruses encoding mammalian cyclin D1 via the tail vein of mice and showed efficient expression of cyclin D1 in liver hepatocytes (Nelsen et al., 2001). 


Nelsen et al., 2001. Transient expression of cyclin D1 is sufficient to promote hepatocyte replication and liver growth in vivo. Cancer Res. 61(23), 8564-8. PMID-11731443; Full-Text Links: aacrjournals, silverchair

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