Category: Database: Disease

Spinocerebellar Ataxia

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Spinocerebellar ataxias (SCAs) are a diverse group of hereditary, progressive neurodegenerative disorders primarily affecting the cerebellum and its connections, leading…

Myotonic Dystrophy

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Myotonic dystrophy (DM) is a multisystemic, inherited neuromuscular disorder and the most common form of adult-onset muscular dystrophy.  It is…

Fragile X Syndrome 

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Fragile X syndrome (FXS) is the most common inherited cause of intellectual disability and a leading single-gene cause of autism…

Trinucleotide Repeat Disorder

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A trinucleotide repeat disorder is a type of genetic condition caused by an abnormal expansion of a sequence of three…

Polyalanine Tract Disorder

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A polyalanine tract disorder refers to a group of genetic conditions caused by abnormal expansions of polyalanine (polyA) tracts within…

Hand–Foot–Genital Syndrome

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Hand–Foot–Genital Syndrome is a rare genetic disorder characterized by congenital malformations affecting the limbs and the genitourinary tract. It belongs…

Polyglutamine Disease

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Polyglutamine (polyQ) diseases are a group of inherited neurodegenerative disorders caused by abnormal expansions of CAG trinucleotide repeats in specific…

Polyglutamine Tract

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Polyglutamine (polyQ) tracts are stretches of multiple glutamine amino acids repeated in sequence within proteins. These regions are encoded by…

Chorea

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Chorea is a neurological movement disorder characterized by brief, irregular, involuntary movements that appear to flow from one muscle to…

Developmental Language Disorder

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Developmental Language Disorder (DLD) is a significant condition that affects language acquisition and use, persisting into adolescence and adulthood. It…

Dyslexia

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Dyslexia is a specific learning disorder that primarily affects the skills involved in accurate and fluent reading and spelling. It…

Agraphia

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Agraphia is a neurological condition characterized by the complete or partial loss of the ability to write, despite having previously…

Dysgraphia

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Dysgraphia is a neurological learning disorder that affects a person’s ability to write coherently, impacting handwriting, spelling, and the ability…

Paragraphia

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Paragraphia is a written language disorder characterized by the impairment of writing abilities, where individuals make specific types of errors…

Anomia

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Anomia is a language disorder characterized by the inability to recall names, words, or specific terms, despite retaining the understanding…